@article{orvain:hal-03844870, TITLE = {{Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models}}, AUTHOR = {Orvain, Cindy and Cauvet, Anne and Prudent, Alexis and Guignabert, Christophe and Thuillet, Rapha{\"e}l and Ottaviani, Mina and Tu, Ly and Duhalde, Fanny and Nicco, Carole and Batteux, Fr{\'e}d{\'e}ric and Avouac, Jerome and Wang, Ning Xin and Seaberg, Michelle A. and Dillon, Stacey R. and Allanore, Yannick}, URL = {https://universite-paris-saclay.hal.science/hal-03844870}, JOURNAL = {{Arthritis Research and Therapy}}, PUBLISHER = {{BioMed Central}}, YEAR = {2022}, DOI = {10.1186/s13075-021-02709-2}, KEYWORDS = {animals ; mice ; humans ; pulmonary hypertension ; fibrosis ; disease models ; animal ; skin ; systemic sclerosis ; transgenic ; pulmonary fibrosis ; cd28 ; scleroderma ; systemic ; icos ; inducible t-cell co-stimulator protein ; costimulation blockade ; dermal fibrosis ; cd28 antigens}, PDF = {https://universite-paris-saclay.hal.science/hal-03844870/file/DOC.pdf}, HAL_ID = {hal-03844870}, HAL_VERSION = {v1}, }