%0 Journal Article %T Final Products of One-Electron Oxidation of Cyclic Dipeptides Containing Methionine Investigated by IRMPD Spectroscopy: Does the Free Radical Choose the Final Compound? %+ Institut de Chimie Physique (ICP) %+ Centre de recherche sur les Ions, les MAtériaux et la Photonique (CIMAP - UMR 6252) %+ Stockholm University %+ Université de Genève = University of Geneva (UNIGE) %+ Chimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques (CSPBAT) %+ Università degli Studi di Roma "La Sapienza" = Sapienza University [Rome] (UNIROMA) %+ Radboud University [Nijmegen] %+ van ‘t Hoff Institute for Molecular Sciences %A Jiang, Yining %A Indrajith, Suvasthika %A Perez Mellor, Ariel Francis %A Bürgi, Thomas %A Lecouvey, Marc %A Clavaguéra, Carine %A Bodo, Enrico %A Houée-Levin, Chantal %A Loire, E. %A Berden, Giel %A Oomens, Jos %A Scuderi, Debora %< avec comité de lecture %Z ICPO_THEOSIM %Z ICPO_CAPRI %Z ICPO_BIO %@ 1520-6106 %J Journal of Physical Chemistry B %I American Chemical Society %V 126 %N 48 %P 10055-10068 %8 2022-12-08 %D 2022 %R 10.1021/acs.jpcb.2c06541 %K One-electron oxidation -radiolysis IRMPD spectroscopy tandem mass spectrometry cyclic peptides %K One-electron oxidation %K -radiolysis %K IRMPD spectroscopy %K tandem mass spectrometry %K cyclic peptides %Z Chemical Sciences/Theoretical and/or physical chemistry %Z Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]Journal articles %X Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) and the hydroxyl radical (• OH) have specific functions in biological processes, while their uncontrolled production and reactivity are known to be determining factors in pathophysiology. Methionine (Met) residues act as endogenous antioxidants, when they are oxidized into methionine sulfoxide (MetSO), thus depleting ROS and protecting the protein. %G English %2 https://universite-paris-saclay.hal.science/hal-04089741/document %2 https://universite-paris-saclay.hal.science/hal-04089741/file/Article_JPCB_revised%20without%20marks.pdf %L hal-04089741 %U https://universite-paris-saclay.hal.science/hal-04089741 %~ CEA %~ UNIV-PARIS13 %~ CNRS %~ INSA-ROUEN %~ COMUE-NORMANDIE %~ INC-CNRS %~ IRAMIS-CIMAP %~ CSPBAT %~ CEA-UPSAY %~ UNIV-PARIS-SACLAY %~ UNIROUEN %~ ENSICAEN %~ UNICAEN %~ INSA-GROUPE %~ SORBONNE-PARIS-NORD %~ UNIVERSITE-PARIS-SACLAY %~ CIMAP %~ IRAMIS %~ GS-CHIMIE %~ GS-PHYSIQUE %~ TEST2-HALCNRS %~ ICPO