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authFullName_s : Ly Tu
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Cibler les ligands du récepteur de l’activine de type IIA pour traiter l’hypertension artérielle pulmonaire

Marc Humbert , David Montani , Laurent Savale , Ly Tu , Christophe Guignabert
Médecine/Sciences, 2021, 37 (10), pp.839-843. ⟨10.1051/medsci/2021131⟩
Journal articles hal-03379128v1
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Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension.

Ly Tu , Laurence Dewachter , Benoit Gore , Elie Fadel , Philippe Dartevelle , et al.
American Journal of Respiratory Cell and Molecular Biology, 2011, 45 (2), pp.311-22. ⟨10.1165/rcmb.2010-0317OC⟩
Journal articles inserm-00579959v1

[IL6R is the key therapeutical target in pulmonary arterial hypertension]

Ly Tu , Carole Phan , Marc Humbert , Christophe Guignabert
Médecine/Sciences, 2018, 34 (10), pp.765-768. ⟨10.1051/medsci/2018201⟩
Journal articles inserm-02580983v1
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T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis

Gonçalo Boleto , Christophe Guignabert , Sonia Pezet , Anne Cauvet , Jérémy Sadoine , et al.
Arthritis Research & Therapy, 2018, 20 (1), pp.197. ⟨10.1186/s13075-018-1694-9⟩
Journal articles hal-03828440v1
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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats Short Title: CXCL12 neutraligands in severe PH in the rat

Jennifer Bordenave , Raphaël Thuillet , Ly Tu , Carole Phan , Amélie Cumont , et al.
Cardiovascular Research, In press, pp.cvz153. ⟨10.1093/cvr/cvz153⟩
Journal articles hal-02195697v1
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Macrophage Migration Inhibitory Factor (MIF) Inhibition in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis

Sven Günther , Jennifer Bordenave , Thông Hua-Huy , Carole Nicco , Amélie Cumont , et al.
International Journal of Molecular Sciences, 2018, 19 (12), pp.4105. ⟨10.3390/ijms19124105⟩
Journal articles inserm-02612651v1
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Additive Protective Effects of Sacubitril/Valsartan and Bosentan on Vascular Remodeling in Experimental Pulmonary Hypertension

Marie-Camille Chaumais , Mohamed Reda Amar Djessas , Raphaël Thuillet , Amélie Cumont , Ly Tu , et al.
Cardiovascular Research, 2020, pp.cvaa200. ⟨10.1093/cvr/cvaa200⟩
Journal articles inserm-02907132v1
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Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension

Zongye Cai , Theo Klein , Laurie Geenen , Ly Tu , Siyu Tian , et al.
Journal of Clinical Medicine, 2020, 9 (5), pp.1248. ⟨10.3390/jcm9051248⟩
Journal articles inserm-02581568v1
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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Ly Tu , Agnes Desroches-Castan , Christine Mallet , Laurent Guyon , Amélie Cumont , et al.
Circulation Research, 2019, 124 (6), pp.846-855. ⟨10.1161/CIRCRESAHA.118.313356⟩
Journal articles inserm-02581297v1
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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery

Heba Abdelazeem , Ly Tu , Raphaël Thuillet , Mina Ottaviani , Achraf Boulfrad , et al.
European Journal of Pharmacology, 2023, 946, pp.175579. ⟨10.1016/j.ejphar.2023.175579⟩
Journal articles inserm-04058680v1
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Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension.

Laurence Dewachter , Serge Adnot , Christophe Guignabert , Ly Tu , Elisabeth Marcos , et al.
European Respiratory Journal, 2009, 34 (5), pp.1100-10. ⟨10.1183/09031936.00183008⟩
Journal articles inserm-00433927v1
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Serum and Pulmonary Uric Acid in Pulmonary Arterial Hypertension

Laurent Savale , Satoshi Akagi , Ly Tu , Amélie Cumont , Raphaël Thuillet , et al.
European Respiratory Journal, 2021, 58 (2), pp.2000332. ⟨10.1183/13993003.00332-2020⟩
Journal articles inserm-03118201v1
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Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension

Alice Huertas , Carole Phan , Jennifer Bordenave , Ly Tu , Raphaël Thuillet , et al.
Chest, 2016, 149 (6), pp.1482-1493. ⟨10.1016/j.chest.2016.01.004⟩
Journal articles inserm-02593143v1
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Innovation thérapeutique dans la dysfonction endothéliale associée à l'hypertension artérielle pulmonaire

Ly Tu
Médecine humaine et pathologie. Université Paris Sud - Paris XI, 2012. Français. ⟨NNT : 2012PA114823⟩
Theses tel-00923004v1
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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells

Benjamin Le Vely , Carole Phan , Nihel Berrebeh , Raphaël Thuillet , Mina Ottaviani , et al.
American Journal of Respiratory Cell and Molecular Biology, 2022, Online ahead of print. ⟨10.1165/rcmb.2021-0332oc⟩
Journal articles inserm-03678207v1

Role for interleukin-6 in COPD-related pulmonary hypertension.

Ari Chaouat , Laurent Savale , Christos Chouaid , Ly Tu , Benjamin Sztrymf , et al.
Chest, 2009, 136 (3), pp.678-87. ⟨10.1378/chest.08-2420⟩
Journal articles hal-00596924v1
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Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

Morane Le Hiress , Ly Tu , Nicolas Ricard , Carole Phan , Raphaël Thuillet , et al.
American Journal of Respiratory and Critical Care Medicine, 2015, 192 (8), pp.983-997. ⟨10.1164/rccm.201402-0322OC⟩
Journal articles inserm-02579320v1
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Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension

Paul-Benoit Poble , Carole Phan , Timothée Quatremare , Jennifer Bordenave , Raphaël Thuillet , et al.
FASEB Journal, 2018, 33 (3), pp.3670-3679. ⟨10.1096/fj.201801659R⟩
Journal articles inserm-02581079v1

Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models

Cindy Orvain , Anne Cauvet , Alexis Prudent , Christophe Guignabert , Raphaël Thuillet , et al.
Arthritis Research & Therapy, 2022, 24 (1), pp.13. ⟨10.1186/s13075-021-02709-2⟩
Journal articles hal-03985048v1

Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling

Kondababu Kurakula , Xiao-Qing Sun , Chris Happé , Denielli da Silva Goncalves Bos , Robert Szulcek , et al.
European Respiratory Journal, 2019, 54 (3), pp.1802400. ⟨10.1183/13993003.02400-2018⟩
Journal articles inserm-02612640v1
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Nouveau regard sur la physiopathologie de l’hypertension artérielle pulmonaire

Jennifer Bordenave , Ly Tu , Laurent Savale , Alice Huertas , Marc Humbert , et al.
Revue des Maladies Respiratoires, 2019, 36 (4), pp.433-437. ⟨10.1016/j.rmr.2019.03.003⟩
Journal articles inserm-02454990v1
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Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension.

Alice Huertas , Ly Tu , Natalia Gambaryan , Barbara Girerd , Frédéric Perros , et al.
European Respiratory Journal, 2012, 40 (4), pp.895-904. ⟨10.1183/09031936.00159911⟩
Journal articles inserm-00913076v1
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Mineralocorticoid Receptor Antagonism by Finerenone Attenuates Established Pulmonary Hypertension in Rats.

Ly Tu , Raphaël Thuillet , Julie Perrot , Mina Ottaviani , Emy Ponsardin , et al.
Hypertension, 2022, pp.101161HYPERTENSIONAHA12219207. ⟨10.1161/HYPERTENSIONAHA.122.19207⟩
Journal articles inserm-03755156v1
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Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22alpha-targeted overexpression of the serotonin transporter.

Christophe Guignabert , Ly Tu , Mohamed Izikki , Laurence Dewachter , Patricia Zadigue , et al.
FASEB Journal, 2009, 23 (12), pp.4135-47. ⟨10.1096/fj.09-131664⟩
Journal articles inserm-00499630v1
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Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension

Véronique Freund-Michel , Marcelina Cardoso dos Santos , Christophe Guignabert , David Montani , Carole Phan , et al.
American Journal of Respiratory and Critical Care Medicine, 2015, 192, pp.342 - 355. ⟨10.1164/rccm.201410-1851oc⟩
Journal articles hal-03329041v1

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

Yuichi Tamura , Carole Phan , Ly Tu , Morane Le Hiress , Raphaël Thuillet , et al.
Journal of Clinical Investigation, 2018, 128 (5), pp.1956-1970. ⟨10.1172/JCI96462⟩
Journal articles inserm-02580448v1
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Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension

Tinne Mertens , Ankit Hanmandlu , Ly Tu , Carole Phan , Scott Collum , et al.
Frontiers in Physiology, 2018, 9, pp.555. ⟨10.3389/fphys.2018.00555⟩
Journal articles inserm-02580921v1
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Platelet‐Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

Julien Solinc , Jessica Raimbault‐machado , France Dierick , Lamiaa El Bernoussi , Ly Tu , et al.
Journal of the American Heart Association, 2022, ⟨10.1161/JAHA.121.023021⟩
Journal articles hal-03629264v1

Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Ly Tu , Agnes Desroches-Castan , Christine Mallet , Laurent Guyon , Amélie Cumont , et al.
Circulation Research, 2019
Journal articles hal-02007505v1

Chronic Inflammation Within the Vascular Wall in Pulmonary Arterial Hypertension: More than a Spectator

Alice Huertas , Ly Tu , Marc Humbert , Christophe Guignabert
Cardiovascular Research, 2019, pp.cvz308. ⟨10.1093/cvr/cvz308⟩
Journal articles inserm-02454983v1