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authFullName_s : Raphaël Thuillet
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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats Short Title: CXCL12 neutraligands in severe PH in the rat

Jennifer Bordenave , Raphaël Thuillet , Ly Tu , Carole Phan , Amélie Cumont , et al.
Cardiovascular Research, In press, pp.cvz153. ⟨10.1093/cvr/cvz153⟩
Journal articles hal-02195697v1
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Macrophage Migration Inhibitory Factor (MIF) Inhibition in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis

Sven Günther , Jennifer Bordenave , Thông Hua-Huy , Carole Nicco , Amélie Cumont , et al.
International Journal of Molecular Sciences, 2018, 19 (12), pp.4105. ⟨10.3390/ijms19124105⟩
Journal articles inserm-02612651v1
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Additive Protective Effects of Sacubitril/Valsartan and Bosentan on Vascular Remodeling in Experimental Pulmonary Hypertension

Marie-Camille Chaumais , Mohamed Reda Amar Djessas , Raphaël Thuillet , Amélie Cumont , Ly Tu , et al.
Cardiovascular Research, 2020, pp.cvaa200. ⟨10.1093/cvr/cvaa200⟩
Journal articles inserm-02907132v1
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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Ly Tu , Agnes Desroches-Castan , Christine Mallet , Laurent Guyon , Amélie Cumont , et al.
Circulation Research, 2019, 124 (6), pp.846-855. ⟨10.1161/CIRCRESAHA.118.313356⟩
Journal articles inserm-02581297v1
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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery

Heba Abdelazeem , Ly Tu , Raphaël Thuillet , Mina Ottaviani , Achraf Boulfrad , et al.
European Journal of Pharmacology, 2023, 946, pp.175579. ⟨10.1016/j.ejphar.2023.175579⟩
Journal articles inserm-04058680v1
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Serum and Pulmonary Uric Acid in Pulmonary Arterial Hypertension

Laurent Savale , Satoshi Akagi , Ly Tu , Amélie Cumont , Raphaël Thuillet , et al.
European Respiratory Journal, 2021, 58 (2), pp.2000332. ⟨10.1183/13993003.00332-2020⟩
Journal articles inserm-03118201v1
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Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension

Alice Huertas , Carole Phan , Jennifer Bordenave , Ly Tu , Raphaël Thuillet , et al.
Chest, 2016, 149 (6), pp.1482-1493. ⟨10.1016/j.chest.2016.01.004⟩
Journal articles inserm-02593143v1
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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells

Benjamin Le Vely , Carole Phan , Nihel Berrebeh , Raphaël Thuillet , Mina Ottaviani , et al.
American Journal of Respiratory Cell and Molecular Biology, 2022, Online ahead of print. ⟨10.1165/rcmb.2021-0332oc⟩
Journal articles inserm-03678207v1
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Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

Morane Le Hiress , Ly Tu , Nicolas Ricard , Carole Phan , Raphaël Thuillet , et al.
American Journal of Respiratory and Critical Care Medicine, 2015, 192 (8), pp.983-997. ⟨10.1164/rccm.201402-0322OC⟩
Journal articles inserm-02579320v1
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Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension

Paul-Benoit Poble , Carole Phan , Timothée Quatremare , Jennifer Bordenave , Raphaël Thuillet , et al.
FASEB Journal, 2018, 33 (3), pp.3670-3679. ⟨10.1096/fj.201801659R⟩
Journal articles inserm-02581079v1

Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models

Cindy Orvain , Anne Cauvet , Alexis Prudent , Christophe Guignabert , Raphaël Thuillet , et al.
Arthritis Research & Therapy, 2022, 24 (1), pp.13. ⟨10.1186/s13075-021-02709-2⟩
Journal articles hal-03985048v1
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Mineralocorticoid Receptor Antagonism by Finerenone Attenuates Established Pulmonary Hypertension in Rats.

Ly Tu , Raphaël Thuillet , Julie Perrot , Mina Ottaviani , Emy Ponsardin , et al.
Hypertension, 2022, pp.101161HYPERTENSIONAHA12219207. ⟨10.1161/HYPERTENSIONAHA.122.19207⟩
Journal articles inserm-03755156v1

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

Yuichi Tamura , Carole Phan , Ly Tu , Morane Le Hiress , Raphaël Thuillet , et al.
Journal of Clinical Investigation, 2018, 128 (5), pp.1956-1970. ⟨10.1172/JCI96462⟩
Journal articles inserm-02580448v1
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Platelet‐Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

Julien Solinc , Jessica Raimbault‐machado , France Dierick , Lamiaa El Bernoussi , Ly Tu , et al.
Journal of the American Heart Association, 2022, ⟨10.1161/JAHA.121.023021⟩
Journal articles hal-03629264v1

Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Ly Tu , Agnes Desroches-Castan , Christine Mallet , Laurent Guyon , Amélie Cumont , et al.
Circulation Research, 2019
Journal articles hal-02007505v1
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Lineage Tracing Reveals the Dynamic Contribution of Pericytes to the Blood Vessel Remodeling in Pulmonary Hypertension

Jennifer Bordenave , Ly Tu , Nihel Berrebeh , Raphaël Thuillet , Amélie Cumont , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (3), pp.766-782. ⟨10.1161/ATVBAHA.119.313715⟩
Journal articles inserm-02454982v2

AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery

Heba Abdelazeem , Ly Tu , Raphaël Thuillet , Mina Ottaviani , Achraf Boulfrad , et al.
European Journal of Pharmacology, 2023, 946, pp.175579. ⟨10.1016/j.ejphar.2023.175579⟩
Journal articles hal-04088740v1
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Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models

Cindy Orvain , Anne Cauvet , Alexis Prudent , Christophe Guignabert , Raphaël Thuillet , et al.
Arthritis Research and Therapy, 2022, ⟨10.1186/s13075-021-02709-2⟩
Journal articles hal-03844870v1
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IL ‐2‐related regulatory CD4 T‐cell deficiency leads to the development of lung fibrosis and vascular remodeling

Camelia Frantz , Anne Cauvet , Aurélie Durand , Virginie Gonzalez , Rémi Pierre , et al.
Arthritis & rheumatology, 2022, Online ahead of print. ⟨10.1002/art.42111⟩
Journal articles inserm-03652770v1

Connexin 43 Is a Promising Target for Pulmonary Hypertension due To Hypoxemic Lung Disease

Claire Bouvard , Nafiisha Genet , Baptiste Rode , Raphaël Thuillet , Ly Tu , et al.
European Respiratory Journal, 2020, 55 (3), pp.1900169. ⟨10.1183/13993003.00169-2019⟩
Journal articles hal-02430904v1

Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

Christophe Guignabert , Carole Phan , Andrei Seferian , Alice Huertas , Ly Tu , et al.
Journal of Clinical Investigation, 2016, 126 (9), pp.3207-3218. ⟨10.1172/JCI86249⟩
Journal articles inserm-02579754v1
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Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension

Nicolas Ricard , Ly Tu , Morane Le Hiress , Alice Huertas , Carole Phan , et al.
Circulation, 2014, 129 (15), pp.1586-1597. ⟨10.1161/CIRCULATIONAHA.113.007469⟩
Journal articles inserm-02578269v1